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COVID-19 pandemic risks global health infrastructure
A new report has found that the COVID-19 pandemic is putting health infrastructure around the world at risk.
The report, released by the non-profit Global...
Pritelivir Phase III clinical trials for HSV immunocompromised patients
The medicine Pritelivir is to enter Phase III clinical trials for the treatment of immunocompromised patients who have acyclovir-resistant mucocutaneous herpes simplex virus (HSV)...
AstraZeneca to test component of Russia’s Sputnik V vaccine
AstraZeneca will be testing a component of Russia’s Sputnik V COVID-19 vaccine in clinical trials of its own vaccine against the virus.
Following the preliminary...
Clinical trial investigates COVID-19 protection for health professionals
Healthcare professionals in the UK will be taking part in a clinical trial to test the efficacy of Carragelose nasal spray for COVID-19 protection.
To...
Clinical trial explores psychedelic treatments for PTSD in veterans
A company exploring the efficacy of psychedelic treatments for PTSD in veterans has announced the international expansion of its Phase 2A clinical trials.
The Mydecine...
Nasal spray clinical trial to investigate prevention of COVID-19 infection
A randomised, double blind trial will be testing the efficacy of a nasal spray to protect frontline healthcare workers against COVID-19.
The spray is the...
Oxford COVID-19 vaccine shows promising results in older adults
Phase II of the Oxford vaccine trial has shown promising safety results in older adults, finding it provokes an immune response.
The early stage results,...
Potential new medicine shows promise for patients with severe asthma
AstraZeneca and Amgen have announced positive results from the NAVIGATOR Phase III trial for a potential new medicine that could help patients with severe,...
Next-generation immunotherapy against cancer enters clinical trials
Scientists have developed a new experimental drug that aims to use the body’s immune system in a response against cancer, which is now entering...
Trial shows positive results for reducing burden of stroke disability
Detailed results from an exploratory analysis of the THALES Phase III trial showed the medication Brilinta (ticagrelor) reduced the rate of the composite of...
Sex differences and women’s representation in clinical trials
Professors Irving Zucker and Brian J Prendergast tell us about the impacts on women of sex biases in clinical drug trials.
In 1993, the US...
Potential lupus treatment reduces organ damaging corticosteroid use
The treatment anifrolumab has been found to reduce lupus flares whilst allowing for patients to reduce the use of corticosteroids that can cause organ...
Psychedelics association to bridge medical establishment and industry gap
Leaders in the field of psychedelic medicine have joined forces to create the global Psychedelic Medicine Association (PMA), which aims to bridge the gap...
Exploring real world applications of cannabis
Dr Hance Clarke tells MCN about the Medical Cannabis Real-World Evidence clinical trial.
Dr Hance Clarke, MSc, MD, PhD, FRCPC is the Medical Director of...
First medicine to prolong survival in patients with chronic kidney disease
In a groundbreaking Phase III trial AstraZeneca’s Farxiga has shown reduction in the risk of kidney failure and cardiovascular or renal death in patients...
Clinical trial shows potential of cannabis to lessen sickle cell disease pain
In a first of its kind clinical trial using gold-standard methods, cannabis has been shown to mitigate the pain of sickle cell disease.
People who...
First at-home treatment for spinal muscular atrophy approved by FDA
The first at-home, orally administered treatment for spinal muscular atrophy has been approved by the US Food and Drug Administration (FDA).
The treatment – Evrysdi...
Farxiga meets endpoints in trial for the treatment of chronic kidney disease
Farxiga has been shown to significantly reduce the worsening of renal function or risk of death in patients with chronic kidney disease with and...
Farxiga granted Fast Track Designation for heart failure treatment
The drug Farxiga has been granted Fast Track Designation in the US for evaluation in the treatment of heart failure.
AstraZeneca has been granted Fast...
Study shows triple-combination therapy reduces COPD exacerbations
Results from a Phase III trial have shown how a triple-combination therapy reduces the rate of moderate or severe COPD exacerbations.
The results from the...